nordihydroguiaretic acid

Ligand id: 4265

Name: nordihydroguiaretic acid

Abbreviated name: NDGA

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 0
Hydrogen bond donors 4
Rotatable bonds 5
Topological polar surface area 80.92
Molecular weight 302.15
XLogP 5.06
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Bioactivity Comments
As we are unable to substantiate the MMOA of this drug we have not tagged a primary drug target.
Selectivity at human ion channels
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
VRAC Channel blocker - - - -
Ligand mentioned in the following text fields