SNX482   Click here for help

GtoPdb Ligand ID: 4315

Synonyms: SNX-482 | toxin SNX-482
Comment: From the venom gland of Hysterocrates gigas (African tarantula)
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Selectivity at ion channels
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
Cav2.3 Hs Gating inhibitor Antagonist 7.5 – 8.0 pIC50 - 2
pIC50 7.5 – 8.0 (IC50 3x10-8 – 1.5x10-8 M) [2]
Voltage: Physiological
Cav2.3 Rn Gating inhibitor Antagonist 7.1 – 8.2 pIC50 - 1,3
pIC50 7.1 – 8.2 [1,3]
Voltage: -90.0 mV