[3H]CGS8216

Ligand id: 4366

Name: [3H]CGS8216    

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 1
Topological polar surface area 45.23
Molecular weight 261.09
XLogP 4.66
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Selectivity at human ion channels
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
GABAA receptor α1 subunit Allosteric modulator Mixed - - -
[Binds to: benzodiazepine site] agonist and antagonist
GABAA receptor α2 subunit Allosteric modulator Mixed - - -
[Binds to: benzodiazepine site] agonist and antagonist
GABAA receptor α3 subunit Allosteric modulator Mixed - - -
[Binds to: benzodiazepine site] agonist and antagonist
GABAA receptor α4 subunit Allosteric modulator Mixed - - -
[Binds to: benzodiazepine site] agonist and antagonist
GABAA receptor α5 subunit Allosteric modulator Mixed - - -
[Binds to: benzodiazepine site] agonist and antagonist
GABAA receptor α6 subunit Allosteric modulator Mixed - - -
[Binds to: benzodiazepine site] agonist and antagonist