draflazine

Ligand id: 4590

Name: draflazine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 12
Topological polar surface area 104.69
Molecular weight 603.2
XLogP 5.75
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human transporters
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
Equilibrative nucleoside transporter 1 Inhibitor Inhibition 9.6 pKi - 2
pKi 9.6 (Ki 2.8x10-10 M) [2]
Targets where the ligand is described in the comment field
Target Comment