Ligand Id: 4733
Ligand name dehydroascorbic acid

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 2
Topological polar surface area 100.9
Molecular weight 174.02
XLogP -1.88
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Summary Biological activity References Structure Similar ligands
Transporters
Transporter DB page EC number Reaction Reference
Glucose transporter 1 View in GRAC 1
Glucose transporter 10 View in GRAC 2
Sodium-dependent vitamin C transporter 1 View in GRAC 3
Sodium-dependent vitamin C transporter 2 View in GRAC 3

Selectivity data from the Guide to Receptors and Channels (GRAC), 5th Edition.

Rank order of potency at human receptors (unless otherwise stated)
Description Rank order of potency Reference
Substrates at Sodium-dependent vitamin C transporter 1 L-ascorbic acid > D-ascorbic acid > dehydroascorbic acid 3
Substrates at Sodium-dependent vitamin C transporter 2 L-ascorbic acid > D-ascorbic acid > dehydroascorbic acid 3

Please note: The activity data given on this ligand page represents selected literature values and may not include all reported data.
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