Ligand Id: 4756
Ligand name LU32-176B

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 2
Rotatable bonds 7
Topological polar surface area 58.29
Molecular weight 398.18
XLogP 6.44
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Summary Biological activity References Structure Similar ligands

Selectivity data from the Guide to Receptors and Channels (GRAC), 5th Edition.

Selectivity at human targets (unless otherwise stated)
Key to terms and symbols Click column headers to sort
Receptor Type Action Affinity Units Concentration range (M) Reference
BGT1 Inhibitor Inhibition 4.0 pIC50 -
GAT1 Inhibitor Inhibition 5.4 pIC50 -

Please note: The activity data given on this ligand page represents selected literature values and may not include all reported data.
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