sulfasalazine

Ligand id: 4840

Name: sulfasalazine

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 3
Rotatable bonds 6
Topological polar surface area 149.69
Molecular weight 398.07
XLogP 4.29
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Bioactivity Comments
As we are unable to substantiate the MMOA of this drug we have not tagged a primary drug target.
Selectivity at transporters
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
Proton-coupled folate transporter Hs Inhibitor Inhibition 4.2 pIC50 - 1
pIC50 4.2 (IC50 6x10-5 M) [1]