activin B   Click here for help

GtoPdb Ligand ID: 4859

Compound class: Endogenous peptide in human, mouse or rat
Comment: Homodimeric endogenous peptide consisting of two subunit chains of inhibin βB. Interacts with activin type I and II receptors.
Species: Human
Natural/Endogenous Targets
Target
Activin receptors
Selectivity at catalytic receptors
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
Activin receptors Ligand is endogenous in the given species Hs Agonist Agonist - - -
⤷
Other ligands which bind to or alter the activity of this ligand
Key to terms and symbols Click column headers to sort
Ligand Sp. Type Action Value Parameter Concentration range (M) Reference
luspatercept Peptide Approved drug Hs Fusion protein Binding 9.2 pKd - 1
⤷ pKd 9.2 (Kd 6.2x10-10 M) [1]
Description: Binding to activin B determined by surface plasmon resonance (SPR).