rho-TIA   Click here for help

GtoPdb Ligand ID: 507

Abbreviated name: ρ-TIA
Synonyms: ρ-TIA conotoxin | 19-amino acid conopeptide | rho-conotoxin TIA
Comment: From Conus tulipa (Fish-hunting cone snail or Tulip cone)
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Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
α1B-adrenoceptor Hs Antagonist Antagonist 8.4 pKi - 1
pKi 8.4 [1]
α1A-adrenoceptor Rn Allosteric modulator Negative 5.0 pKi - 3
pKi 5.0 (Ki 1x10-5 M) [3]
α1B-adrenoceptor Rn Allosteric modulator Negative 9.1 pIC50 - 2
pIC50 9.1 (IC50 8x10-10 M) [2]