cilastatin

Ligand id: 5166

Name: cilastatin

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 4
Rotatable bonds 12
Topological polar surface area 155.02
Molecular weight 358.16
XLogP -0.52
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at unknown species enzymes
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Target Type Action Affinity Units Concentration range (M) Reference
Dipeptidase 1 Inhibitor Inhibition 6.0 pKi - 1
pKi 6.0 (Ki 1.1x10-6 M) [1]