Ligand id: 5168

Name: cinaciguat

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 17
Topological polar surface area 87.07
Molecular weight 565.28
XLogP 11.51
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at enzymes
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
Guanylyl cyclase, α1β1 Hs Activator Activation - - - 1
[Binds to: apo-GC-1] [1]
Guanylyl cyclase, α2β1 Hs Activator Activation - - - 1
[Binds to: apo-GC-2] [1]