Ligand id: 5285

Name: vinpocetine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Topological polar surface area 34.47
Molecular weight 350.2
XLogP 5.12
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at enzymes
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
phosphodiesterase 1A Hs Inhibitor Inhibition 5.1 pIC50 - 2
pIC50 5.1 (IC50 7.94x10-6 M) [2]
phosphodiesterase 1C Hs Inhibitor Inhibition 4.3 pIC50 - 2
pIC50 4.3 (IC50 5.01x10-5 M) [2]