compound 5g [PMID: 21571530]

Ligand id: 5514

Name: compound 5g [PMID: 21571530]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 9
Topological polar surface area 80.91
Molecular weight 458.14
XLogP 5.9
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
succinate receptor Hs Antagonist Antagonist 7.5 pIC50 - 1
pIC50 7.5 (IC50 3.5x10-8 M) [1]
succinate receptor Rn Antagonist Antagonist 6.9 pIC50 - 1
pIC50 6.9 (IC50 1.35x10-7 M) [1]