YSFKPMPLaR   Click here for help

GtoPdb Ligand ID: 5776

Synonyms: C5a65-74Y65,F67,P69,P71,D-Ala73
Comment: Synthetic analogue of human C5a
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Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
C3a receptor Hs Agonist Full agonist 6.7 pEC50 - 2
pEC50 6.7 (EC50 2.2x10-7 M) [2]
C5a1 receptor Hs Agonist Agonist 5.5 pEC50 - 3
pEC50 5.5 (EC50 3.24x10-6 M) [3]
C5a1 receptor Hs Agonist Full agonist 5.4 – 6.7 pIC50 - 1
pIC50 5.4 – 6.7 (IC50 4.2x10-6 – 2x10-7 M) [1]