EP 157

Ligand id: 5853

Name: EP 157

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 11
Topological polar surface area 58.89
Molecular weight 443.25
XLogP 10.62
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
IP receptor Agonist Full agonist 4.9 – 5.7 pIC50 - 1
pIC50 4.9 – 5.7 (IC50 1.12x10-5 – 2.03x10-6 M) [1]