candesartan

Ligand id: 587

Name: candesartan

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 2
Rotatable bonds 7
Topological polar surface area 118.81
Molecular weight 440.16
XLogP 6.89
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
AT1 receptor Antagonist Antagonist 9.5 – 9.7 pIC50 - 2
pIC50 9.5 – 9.7 (IC50 3.2x10-10 – 1.9x10-10 M) [2]
Targets where the ligand is described in the comment field
Target Comment
Ligand mentioned in the following text fields