IL-17C   Click here for help

GtoPdb Ligand ID: 5875

Synonyms: cytokine CX2 | interleukin-17C
Immunopharmacology Ligand
Comment: IL-17C is an IL-17 homolog, secreted by epithelial cells in response to bacterial challenge and inflammatory stimuli and that acts in an autocrine manner to control the innate epithelial immune responses necessary for regulating intestinal inflammation and barrier function [1-2].
Species: Human
Natural/Endogenous Targets
Target
Interleukin-17C receptor
Selectivity at catalytic receptors
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
Interleukin-17C receptor Ligand is endogenous in the given species Hs Agonist Agonist - - -