AG 112

Ligand id: 5913

Name: AG 112

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 2
Topological polar surface area 117.62
Molecular weight 236.07
XLogP 1.06
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at catalytic receptors
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
epidermal growth factor receptor Hs Inhibitor Inhibition 6.9 pIC50 - 3
pIC50 6.9 (IC50 1.25x10-7 M) [3]
Description: Measuring inhibition of substrate phosphorylation.