AGL 2043

Ligand id: 5918

Name: AGL 2043

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 1
Topological polar surface area 71.84
Molecular weight 280.08
XLogP 3.15
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human catalytic receptors
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
platelet derived growth factor receptor beta Inhibitor Inhibition 7.1 pIC50 - 3
pIC50 7.1 (IC50 9x10-8 M) [3]
Description: Using purified human PDGFRβ