aloisine

Ligand id: 5923

Name: aloisine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 50.8
Molecular weight 281.15
XLogP 4.06
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human enzymes
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
cyclin dependent kinase 2 Inhibitor Inhibition 9.3 pKi - 2
pKi 9.3 (Ki 5.3x10-10 M) [2]
Description: Measuring inhibition of CDK2 in association with cyclin E
protein tyrosine kinase 2 beta Inhibitor Inhibition 6.0 pKi - 2
pKi 6.0 (Ki 9.33x10-7 M) [2]
zeta chain of T-cell receptor associated protein kinase 70 Inhibitor Inhibition 5.6 pKi - 2
pKi 5.6 (Ki 2.63x10-6 M) [2]