bisindolylmaleimide IV

Ligand id: 5937

Name: bisindolylmaleimide IV

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 2
Topological polar surface area 77.75
Molecular weight 327.1
XLogP 3.22
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human enzymes
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Target Type Action Affinity Units Concentration range (M) Reference
protein kinase C beta Inhibitor Inhibition 6.7 pIC50 - 3
pIC50 6.7 (IC50 2.12x10-7 M) [3]
Description: PKCβ2 isoform