Cdc2-like kinase inhibitor

Ligand id: 5942

Name: Cdc2-like kinase inhibitor

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 3
Topological polar surface area 54.84
Molecular weight 249.08
XLogP 2.99
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at mouse enzymes
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
CDC like kinase 1 Inhibitor Inhibition 8.0 pKi - 2
pKi 8.0 (Ki 1x10-8 M) [2]
CDC like kinase 1 Inhibitor Inhibition 7.7 pIC50 - 2
pIC50 7.7 (IC50 2x10-8 M) [2]
CDC like kinase 2 Inhibitor Inhibition 6.7 pIC50 - 2
pIC50 6.7 (IC50 2x10-7 M) [2]