Chk2 inhibitor II

Ligand id: 5954

Name: Chk2 inhibitor II

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 4
Topological polar surface area 81
Molecular weight 363.08
XLogP 4.57
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human enzymes
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
checkpoint kinase 2 Inhibitor Inhibition 7.4 pKi - 2
pKi 7.4 (Ki 3.7x10-8 M) [2]