DNA-PK inhibitor V

Ligand id: 5961

Name: DNA-PK inhibitor V

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 3
Topological polar surface area 49.77
Molecular weight 283.12
XLogP 3.71
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human enzymes
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Target Type Action Affinity Units Concentration range (M) Reference
DNA-dependent protein kinase catalytic subunit Inhibitor Inhibition 6.6 pIC50 - 2
pIC50 6.6 (IC50 2.7x10-7 M) [2]