cholic acid

Ligand id: 609

Name: cholic acid

Abbreviated name: CA

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 4
Rotatable bonds 4
Topological polar surface area 97.99
Molecular weight 408.29
XLogP 4.09
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Natural/Endogenous Targets
Target
GPBA receptor
Transporters Moving this Compound Across a Lipid Membrane
Transporter EC number Reaction Reference
Sodium/bile acid and sulphated solute cotransporter 1 4
Sodium/bile acid and sulphated solute cotransporter 2 1
Selectivity at human GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
GPBA receptor Agonist Full agonist 5.0 pEC50 - 3
pEC50 5.0 [3]
Selectivity at unknown species nuclear hormone receptors
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
Farnesoid X receptor Agonist Agonist 4.0 – 5.0 pEC50 - 5-6
pEC50 4.0 – 5.0 [5-6]
Additional information and targets (data relate to human unless otherwise stated)
Description Data Reference