Ligand id: 6155

Name: CP-195543

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 5
Topological polar surface area 66.76
Molecular weight 428.12
XLogP 7.82
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
BLT1 receptor Hs Antagonist Antagonist 8.2 pKi - 1
pKi 8.2 (Ki 6.8x10-9 M) [1]
BLT2 receptor Hs Agonist Partial agonist <5.0 pEC50 - 2
pEC50 <5.0 (EC50 >1x10-5 M) [2]
BLT1 receptor Hs Antagonist Antagonist 8.6 pIC50 - 1
pIC50 8.6 (IC50 2.4x10-9 M) [1]
BLT2 receptor Hs Antagonist Antagonist 6.0 pIC50 - 2
pIC50 6.0 (IC50 1x10-6 M) [2]