5-(6-chloro-2-hexyl-1H-indol-1-yl)-5-oxo-valeric acid

Ligand id: 6174

Name: 5-(6-chloro-2-hexyl-1H-indol-1-yl)-5-oxo-valeric acid

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 10
Topological polar surface area 59.3
Molecular weight 349.14
XLogP 5.22
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
OXE receptor Hs Antagonist Antagonist 6.4 pIC50 - 1
pIC50 6.4 (IC50 4x10-7 M) [1]