bag-1

Ligand id: 6188

Name: bag-1

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 7
Topological polar surface area 41.57
Molecular weight 333.22
XLogP 7.68
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
BB3 receptor Agonist Agonist 7.7 pIC50 - 1
pIC50 7.7 (IC50 1.83x10-8 M) [1]
Selectivity at mouse GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
BB3 receptor Agonist Full agonist 8.2 pIC50 - 1
pIC50 8.2 (IC50 6.9x10-9 M) [1]
Selectivity at rat GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
BB3 receptor Agonist Full agonist 8.6 pIC50 - 1
pIC50 8.6 (IC50 2.4x10-9 M) [1]