AZ12216052

Ligand id: 6216

Name: AZ12216052

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 8
Topological polar surface area 54.4
Molecular weight 391.06
XLogP 7.37
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
mGlu8 receptor Hs Allosteric modulator Positive 6.0 pEC50 - 1
pEC50 6.0 (EC50 1x10-6 M) [1]