compound 32 [PMID: 19289283]

Ligand id: 6351

Name: compound 32 [PMID: 19289283]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 72.4
Molecular weight 371.23
XLogP 2.26
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at rat GPCRs
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Target Type Action Affinity Units Concentration range (M) Reference
mGlu1 receptor Allosteric modulator Negative 8.2 pIC50 - 1
pIC50 8.2 (IC50 6x10-9 M) [1]