compound 10i [PMID: 23084894]

Ligand id: 6365

Name: compound 10i [PMID: 23084894]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 95.59
Molecular weight 365.09
XLogP 2.21
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human GPCRs
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Target Type Action Affinity Units Concentration range (M) Reference
mGlu1 receptor Allosteric modulator Negative 8.2 pIC50 - 1
pIC50 8.2 (IC50 6x10-9 M) [1]