compound 47 [PMID: 21295468]

Ligand id: 6406

Name: compound 47 [PMID: 21295468]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 3
Topological polar surface area 34.59
Molecular weight 256.12
XLogP 2.89
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
mGlu5 receptor Allosteric modulator Positive 7.3 pEC50 - 1
pEC50 7.3 (EC50 5.01x10-8 M) [1]