bis-triazole derivative 10

Ligand id: 6537

Name: bis-triazole derivative 10

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 15
Hydrogen bond donors 5
Rotatable bonds 9
Topological polar surface area 224.04
Molecular weight 681.26
XLogP 4.62
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at enzymes
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
plasminogen Hs Inhibitor Inhibition 9.1 pKi - 1
pKi 9.1 (Ki 7.7x10-10 M) [1]