tirofiban

Ligand id: 6586

Name: tirofiban

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 3
Rotatable bonds 14
Topological polar surface area 113.11
Molecular weight 440.23
XLogP 4.01
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human catalytic receptors
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
integrin αIIbβ3 Inhibitor Inhibition 9.4 pIC50 - 1
pIC50 9.4 (IC50 3.7x10-10 M) [1]
Description: Displacement of biotinylated fibrinogen from human integrin αIIbβ3.