icatibant

Ligand id: 667

Name: icatibant

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human GPCRs
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Target Type Action Affinity Units Concentration range (M) Reference
B2 receptor Antagonist Antagonist 8.4 pA2 - 6
pA2 8.4 [6]
B2 receptor Antagonist Antagonist 10.2 pKi - 1
pKi 10.2 (Ki 6.4x10-11 M) [1]
B1 receptor Antagonist Antagonist 6.4 – 7.0 pKi - 3,8
pKi 6.4 – 7.0 [3,8]
B2 receptor Antagonist Antagonist 8.0 – 9.4 pIC50 - 2,7
pIC50 8.0 – 9.4 [2,7]
Selectivity at mouse GPCRs
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Target Type Action Affinity Units Concentration range (M) Reference
B2 receptor Antagonist Antagonist 9.6 pKi - 7
pKi 9.6 [7]
Selectivity at rat GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
B2 receptor Antagonist Antagonist 10.0 – 10.3 pKi - 4
pKi 10.0 – 10.3 [4]
B1 receptor Antagonist Antagonist 6.1 – 6.4 pKi - 8
pKi 6.1 – 6.4 [8]