prinaberel

Ligand id: 6700

Name: prinaberel

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 2
Rotatable bonds 2
Topological polar surface area 66.49
Molecular weight 271.06
XLogP 3.23
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at nuclear hormone receptors
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
Estrogen receptor-β Rn Agonist Agonist 8.5 pIC50 - 2
pIC50 8.5 (IC50 3.1x10-9 M) [2]
Estrogen receptor-β Mm Agonist Agonist 8.4 pIC50 - 2
pIC50 8.4 (IC50 3.7x10-9 M) [2]
Estrogen receptor-β Hs Agonist Agonist 8.3 pIC50 - 2,4
pIC50 8.3 (IC50 5x10-9 M) [2,4]
Estrogen receptor-α Rn Agonist Agonist 6.2 pIC50 - 2
pIC50 6.2 (IC50 6.2x10-7 M) [2]
Estrogen receptor-α Mm Agonist Agonist 6.1 pIC50 - 2
pIC50 6.1 (IC50 7.5x10-7 M) [2]
Estrogen receptor-α Hs Agonist Agonist 5.9 pIC50 - 2
pIC50 5.9 (IC50 1.216x10-6 M) [2]