compound 26c [PMID: 16242323]

Ligand id: 6734

Name: compound 26c [PMID: 16242323]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 15
Topological polar surface area 109.58
Molecular weight 723.37
XLogP 12.43
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at rat enzymes
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
acetyl-CoA acetyltransferase 1 Inhibitor Inhibition 6.3 pIC50 - 1
pIC50 6.3 (IC50 5.4x10-7 M) [1]