certolizumab pegol

Ligand id: 6774

Name: certolizumab pegol

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Bioactivity Comments
Certolizumab pegol neutralises soluble TNFα in vitro, with an IC90 of 3ng/ml [2], neutralises the effects mediated by membrane bound TNFα, and inhibits production of IL-1β in monocytes stimulated with LPS.
Selectivity at human ligand targets
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
tumour necrosis factor shed form Antibody Binding - - - 2
[2]
Description: Note IC90 value of 3ng/ml is provided