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Synonyms: CDP 771 | CMA 676 | hP67.6-calicheamicin | Mylotarg® | WAY-CMA 676
gemtuzumab ozogamicin is an approved drug (FDA (2000), EMA (2018))
Compound class:
Antibody
Comment: This drug is an antibody-drug conjugate (ADC) that targets delivery of the highly cytotoxic ozogamicin (a derivative of calicheamicin γ1) to CD33 +ve myeloid cells [1].
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| Bioactivity Comments |
| We have been unable to find publicly available affinity data for the interaction between gemtuzumab and CD33 to substantiate its primary molecular target. |
| Selectivity at other protein targets | ||||||||||||||||||||||||||||||||||
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