drotrecogin alfa

Ligand id: 6788

Name: drotrecogin alfa

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Bioactivity Comments
The molecular mechanism is complex and includes inhibition of coagulation factors Va and VIIIa, but we have been unable to find peer reviewed data to substantiate the molecular interaction.
Selectivity at other protein targets
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
coagulation factor V Hs Antagonist Inhibition - - - 1-2
Antithrombotic effect thought to occur via inhibition of factors Va and VIIIa [1-2]
coagulation factor VIII Hs Antagonist Inhibition - - - 1-2
Antithrombotic effect thought to occur via inhibition of factors Va and VIIIa [1-2]