bradyzide

Ligand id: 680

Name: bradyzide

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 10
Hydrogen bond donors 4
Rotatable bonds 18
Topological polar surface area 192.66
Molecular weight 682.27
XLogP 7.74
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
B2 receptor Antagonist Antagonist 6.3 – 6.5 pKi - 1
pKi 6.3 – 6.5 [1]
Selectivity at rat GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
B2 receptor Antagonist Antagonist 9.2 – 9.5 pKi - 1
pKi 9.2 – 9.5 [1]