finasteride

Ligand id: 6818

Name: finasteride

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 3
Topological polar surface area 58.2
Molecular weight 372.28
XLogP 4.65
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human enzymes
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Target Type Action Affinity Units Concentration range (M) Reference
steroid 5 alpha-reductase 2 Inhibitor Inhibition 7.8 pIC50 - 1
pIC50 7.8 (IC50 1.46x10-8 M) [1]