ribavirin

Ligand id: 6842

Name: ribavirin

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 9
Hydrogen bond donors 4
Rotatable bonds 3
Topological polar surface area 143.72
Molecular weight 244.08
XLogP -3.04
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Transporters Moving this Compound Across a Lipid Membrane
Transporter EC number Reaction Reference
Sodium/nucleoside cotransporter 1 1
Equilibrative nucleoside transporter 1 1
Selectivity at human enzymes
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
inosine monophosphate dehydrogenase 1 Inhibitor Inhibition 5.6 – 6.0 pIC50 - 2
pIC50 5.6 – 6.0 (IC50 2.5x10-6 – 1x10-6 M) [2]
Description: In vitro inhibition of IMPDH (isoform not specified, human and mouse assayed)
inosine monophosphate dehydrogenase 2 Inhibitor Inhibition 5.6 – 6.0 pIC50 - 2
pIC50 5.6 – 6.0 (IC50 2.5x10-6 – 1x10-6 M) [2]
Description: In vitro inhibition of IMPDH (isoform not specified, human and mouse assayed)