trilostane

Ligand id: 6850

Name: trilostane

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 0
Topological polar surface area 76.78
Molecular weight 329.2
XLogP 2.64
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at unknown species enzymes
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Target Type Action Affinity Units Concentration range (M) Reference
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 Inhibitor Inhibition 8.4 pIC50 - 1
pIC50 8.4 (IC50 4x10-9 M) Note that the species is not specified in the referenced article. [1]
Description: In vitro enzyme inhibition