amylin   Click here for help

GtoPdb Ligand ID: 688

Abbreviated name: AMY
Species: Mouse, Rat
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Natural/Endogenous Targets
Target
AMY1 receptor
AMY2 receptor
AMY3 receptor
CT receptor
Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
AMY1 receptor Hs Agonist Full agonist 9.0 – 10.7 pEC50 - 1-4
pEC50 9.0 – 10.7 (EC50 1.047x10-9 – 1.99x10-11 M) [1-4]
AMY3 receptor Hs Agonist Full agonist 8.6 – 10.8 pEC50 - 1-3
pEC50 8.6 – 10.8 [1-3]
AMY2 receptor Hs Agonist Full agonist 8.5 – 9.9 pEC50 - 1-2,4
pEC50 8.5 – 9.9 (EC50 3.388x10-9 – 1.25x10-10 M) [1-2,4]
CT receptor Hs Agonist Full agonist 7.0 – 9.5 pEC50 - 1,3,5
pEC50 7.0 – 9.5 [1,3,5]