bapineuzumab   Click here for help

GtoPdb Ligand ID: 6930

Synonyms: 3D-6 | AAB-001
Compound class: Antibody
Comment: Humanized monoclonal antibody to amyloid β (Aβ). Binds to Aβ deposits and reduces amyloid load primarily through microglial clearance.
Selectivity at ligand targets
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
amyloid β Primary target of this compound Hs Antibody Binding 7.1 pKd - 1-2
⤷ pKd 7.1 (Kd 8.9x10-8 M) Binding of soluble amyloid β(1-40) [1-2]