solanezumab   Click here for help

GtoPdb Ligand ID: 6932

Synonyms: LY-2062430
Compound class: Antibody
Comment: Solanezumab is an investigational humanized monoclonal antibody targeting amyloid-β (Aβ).
Annotated peptide sequences for this antibody are available from its IMGT/mAb-DB record. The invention of solanezumab is covered by patent US7195761 [2], where it is coded as Hu266.
Selectivity at ligand targets
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
amyloid β Primary target of this compound Hs Antibody Binding 10.4 pKd - 2
⤷ pKd 10.4 (Kd 4x10-11 M) [2]
Description: Binding affinity for Aβ1-42 measured using proprietary BIAcore technology