BIX-01294

Ligand id: 7014

Name: BIX-01294

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 7
Topological polar surface area 65.99
Molecular weight 490.31
XLogP 4.26
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human enzymes
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
euchromatic histone lysine methyltransferase 2 Inhibitor Inhibition 5.8 pIC50 - 1
pIC50 5.8 (IC50 1.7x10-6 M) [1]
Description: Antibody-based detection of in vitro methylation.
euchromatic histone lysine methyltransferase 1 Inhibitor Inhibition 4.4 pIC50 - 1
pIC50 4.4 (IC50 3.8x10-5 M) [1]