AR234960

Ligand id: 7039

Name: AR234960

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 8
Topological polar surface area 117.5
Molecular weight 555.2
XLogP 4.58
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
MAS1 Hs Agonist Full agonist 6.1 – 6.5 pEC50 - 1
pEC50 6.1 – 6.5 (EC50 7.2x10-7 – 3.5x10-7 M) [1]
MAS1 Rn Agonist Full agonist 5.8 – 6.8 pEC50 - 1
pEC50 5.8 – 6.8 (EC50 1.71x10-6 – 1.7x10-7 M) [1]