clobetasol propionate

Ligand id: 7062

Name: clobetasol propionate

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 80.67
Molecular weight 466.19
XLogP 2.98
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human nuclear hormone receptors
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Target Type Action Affinity Units Concentration range (M) Reference
Glucocorticoid receptor Agonist Agonist 9.2 pKi - 1
pKi 9.2 (Ki 6.62x10-10 M) [1]